??? ?? ?? ?? ???? ????? ????? ??? ?? ???? ???? ????? ??????? ?????? ???? ??, ?????? ????? ?? ?? ??????????? ??????? ???? ??.The endothelial cells while in the cerebral blood vessel partitions are joined tightly to one another, forming the blood–brain barrier, which blocks the passage of many toxins and pathogens[35] (even though at the same time